Research Associate

About the Role

The University of Manchester is seeking a motivated and collaborative Research Associate to join a translational research project focused on developing a mammalian-produced, bioactive BMP13 (GDF6) reagent for intervertebral disc and cartilage repair. This role offers an exciting opportunity to work at the intersection of regenerative medicine, protein science, and industry collaboration within a dynamic and inclusive environment.

About You

We are looking for individuals with diverse perspectives and experiences. Essential criteria include a PhD (or near completion) in a relevant field such as biochemistry, molecular biology, biotechnology, or regenerative medicine. You should possess hands-on experience in mammalian cell culture and molecular biology techniques, including cloning and construct design. Proficiency in protein analysis methods like SDS-PAGE, Western blotting, and ELISA is required, alongside strong data analysis, organizational, and problem-solving skills. Excellent communication abilities and the capacity to work both independently and collaboratively in a multidisciplinary setting are crucial.

Desirable criteria include experience in mammalian expression optimization, protein purification, and downstream processing. Familiarity with advanced analytical or biophysical techniques (e.g., HPLC, mass spectrometry), experience with translational or industry-linked research, and a track record of contributing to publications, funding applications, or collaborative research outputs are advantageous. Experience supporting students or junior colleagues is also a plus. We value transferable skills and real-world experience equally with formal qualifications.

Responsibilities

• Design and execute experimental studies to advance the development of bioactive BMP13 for regenerative medicine applications.
• Optimize mammalian expression systems, construct design, and protein processing to improve yield and activity.
• Perform protein analysis and bioactivity testing using biochemical and functional assays.
• Analyze and interpret experimental data, maintaining meticulous records and adhering to reproducible research practices.
• Collaborate with academic and industrial partners, contributing to reports, publications, and dissemination activities.

Perks

• Generous employer contribution pension scheme.
• 29 days of annual leave plus bank holidays, in addition to a Christmas closure period.
• Access to 'Ride to Work' and Electric Vehicle (EV) car schemes.

Additional Information

The University of Manchester is committed to fostering an open environment for inquiry and debate, celebrating diversity, and promoting education and learning. We encourage the exploration of new ideas and diverse opinions. For more information on benefits and working here, please visit https://www.manchester.ac.uk/connect/jobs/benefits-working-here/. Information on flexible and hybrid working can be found at https://www.staffnet.manchester.ac.uk/people/current-staff/flexible-and-hybrid-working/. Enquiries about the role can be directed to Dr Stephen Richardson at [email protected]. General enquiries and administrative support can be reached at [email protected]. Technical and job portal support is available at https://jobseekersupport.jobtrain.co.uk/support/home. Applications must be submitted by midnight on the closing date. Further particulars, including a person specification, are available via the link provided.