Process Development Chemist

Role overview

An opportunity is available for a Process Chemist with at least 2 years of GMP industry experience in synthetic chemistry. The role is centred on process optimisation, supporting transfer activities, validating manufacturing changes, and contributing to new product introductions.

What you will do

• Lead workstreams that support team and site goals, as well as agreed project timelines.
• Apply synthetic chemistry knowledge to improve, scale up, and refine manufacturing routes for peptide and small molecule APIs.
• Spot process constraints and inefficiencies early, then drive practical improvements for development and commercial API operations.
• Investigate unplanned events that need chemistry expertise.
• Review technical investigations, including root-cause analysis and suggested corrective and preventive actions.
• Prepare samples and carry out sample analysis where needed, then review data and produce accurate technical reports.
• Document experimental work in controlled notebooks or protocols in line with GxP and data integrity expectations, including ALCOA principles.
• Support capital projects through technical chemistry input, including help with equipment selection, installation, and commissioning.
• Work closely across functions and demonstrate strong cross-functional collaboration.
• Partner with Manufacturing, QA, QC, and APID in an MS&T capacity.
• Build capability in operational excellence tools and apply them across daily work.
• Help design and run continued process verification activities, with a proactive and reactive focus on process improvement.
• Support process validation by preparing validation protocols and summary reports.
• Draft, review, and update key documentation such as SOPs, training materials, protocols, and reports.
• Run DOE studies and define proven acceptable ranges to support regulatory filings.
• Contribute to technology transfer and the introduction of new products from development into commercial manufacturing.
• Represent MS&T professionally in interactions with other departments.
• Take on any other duties or adjusted working practices that may be required as site or business needs change.

Requirements

• Degree-qualified at MSc or BSc level in a scientific, pharmaceutical, or engineering discipline.
• Minimum 2 years of GMP industry experience in synthetic chemistry.
• Practical understanding of product impact assessments, risk assessments, and FMEAs.
• Comfortable working independently and taking initiative.
• Able to organise and prioritise work across several projects at once.
• Strong attention to detail and solid data analysis capability.
• Good grasp of change management.
• Good understanding of continuous improvement methods.
• Clear communicator who writes in a concise and fluent style.

Additional information

This position is based onsite in Dublin, County Dublin, Ireland and is offered on a contract basis. The role requires hands-on support across development and commercial API activities, with regular collaboration across manufacturing and support functions.